STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS75223.1ABC transporter, permease protein; KEGG: cdi:DIP0495 2.8e-09 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; COG: COG0687 Spermidine/putrescine-binding periplasmic protein; Psort location: CytoplasmicMembrane, score: 10.00. (616 aa)    
Predicted Functional Partners:
EDS75224.1
ABC transporter, permease protein; KEGG: hpa:HPAG1_0451 1.5e-09 molybdenum ABC transporter ModB K06022; COG: COG1176 ABC-type spermidine/putrescine transport system, permease component I; Psort location: CytoplasmicMembrane, score: 10.00.
 0.999
potA
Polyamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 0.999
EDS75014.1
KEGG: ava:Ava_0243 1.8e-05 molybdate ABC transporter, permease protein K02018; COG: COG1178 ABC-type Fe3+ transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.923
EDS75226.1
Cupin domain protein; KEGG: pab:PAB0818 0.0061 manC; mannose-1-phosphate guanylyltransferase K00971; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.874
EDS75015.1
KEGG: mcp:MCAP_0202 6.5e-57 spermidine/putrescine ABC transporter, ATP-binding protein K02052; COG: COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Psort location: CytoplasmicMembrane, score: 9.49.
 
   
 0.853
EDS74629.1
Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.656
EDS73788.1
Transcriptional regulator, AraC family; KEGG: bsu:BG10166 1.7e-13 adaA; methylphosphotriester-DNA alkyltransferase / transcriptional regulator (AraC family) K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.65.
 
 
 
 0.643
EDS74589.1
S4 domain protein; KEGG: tma:TM0462 1.2e-06 conserved hypothetical protein K06180; COG: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).
   
    0.627
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
  
  
 0.609
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
  
  
 0.608
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.