STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (404 aa)    
Predicted Functional Partners:
EDS74316.1
Methionine synthase, vitamin-B12 independent; KEGG: lsl:LSL_0129 5.1e-112 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; COG: COG0620 Methionine synthase II (cobalamin-independent); Psort location: Cytoplasmic, score: 8.87.
  
 0.974
EDS75105.1
KEGG: ctc:CTC01806 2.7e-209 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.926
metF
KEGG: mxa:MXAN_3039 1.4e-61 metF; 5,10-methylenetetrahydrofolate reductase; COG: COG0685 5,10-methylenetetrahydrofolate reductase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.868
EDS75035.1
Hypothetical protein; COG: COG1956 GAF domain-containing protein.
    
  0.848
EDS73952.1
Methyltransferase domain protein; KEGG: btk:BT9727_3407 1.6e-23 possible ubiquinone/menaquinone methyltransferase K00599; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.842
cps4K
Capsular polysaccharide biosynthesis protein Cps4K; KEGG: vfi:VF0192 2.6e-60 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
   
 0.835
EDS75171.1
Hypothetical protein; KEGG: vfi:VF0192 0.00030 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases.
   
 0.835
EDS75176.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 4.6e-72 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
   
 0.835
EDS74358.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 6.5e-73 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases.
   
 0.835
coaBC
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 0.804
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.