Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS75283.1Histidine triad domain protein; KEGG: spa:M6_Spy1466 3.6e-33 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) K02503; COG: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; Psort location: Cytoplasmic, score: 8.87. (135 aa)    
Predicted Functional Partners:
lysS
lysine--tRNA ligase; KEGG: gka:GK0074 3.2e-167 lysyl-tRNA synthetase (lysine--tRNA ligase) K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.804
EDS74665.1
Glutamine synthetase, beta-grasp domain protein; KEGG: mma:MM0964 3.0e-91 glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
  
   0.785
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
 
   0.723
EDS75561.1
Hypothetical protein; COG: NOG11764 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
   0.716
EDS75281.1
PPIC-type PPIASE domain protein; KEGG: ser:SERP1376 1.1e-19 protein export protein PrsA, putative K01802; COG: COG0760 Parvulin-like peptidyl-prolyl isomerase.
  
   0.714
EDS75282.1
Hypothetical protein; KEGG: smu:SMU.648 7.3e-10 prtM; putative protease maturation protein precursor K07533; COG: COG0760 Parvulin-like peptidyl-prolyl isomerase.
  
   0.659
EDS75995.1
Transcriptional regulator, Sir2 family; KEGG: tte:TTE1570 7.9e-13 sir2; NAD-dependent protein deacetylase, Sir2 family K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.592
EDS74705.1
Hypothetical protein; KEGG: hit:NTHI1634 2.3e-14 NAD-dependent deacetylase sirtuin 5 K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family.
  
 
  0.592
EDS74860.1
KEGG: spr:spr1354 5.2e-24 glnQ; ABC transporter ATP-binding protein - glutamine transport K02028; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.483
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
  
 0.449
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (16%) [HD]