STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recXRegulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. (668 aa)    
Predicted Functional Partners:
EDS75287.1
Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
 
0.977
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
 
 0.922
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.919
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.911
EDS75543.1
Lipid kinase, YegS/Rv2252/BmrU family; KEGG: eci:UTI89_C2362 2.6e-17 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.
  
 
 0.847
EDS75268.1
KEGG: oih:OB1952 2.4e-20 dgkA; diacylglycerol kinase K00901; COG: COG0818 Diacylglycerol kinase.
    
 0.836
EDS75284.1
Nucleic acid-binding domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87.
  
    0.823
EDS74493.1
Diacylglycerol kinase catalytic domain protein; KEGG: eci:UTI89_C2362 1.2e-09 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.820
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.658
EDS73937.1
Glycosyltransferase, group 1 family protein; KEGG: pub:SAR11_0559 7.0e-15 rfaK; 1,2-N-acetylglucosaminetransferase; COG: COG0438 Glycosyltransferase; Psort location: CytoplasmicMembrane, score: 9.75.
 
 
  0.658
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.