| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS74547.1 | EDS75287.1 | CLOSPI_01602 | CLOSPI_01138 | Hypothetical protein; KEGG: sbo:SBO_2558 0.0059 putative enzyme; COG: COG1073 Hydrolases of the alpha/beta superfamily. | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.411 |
| EDS74547.1 | recX | CLOSPI_01602 | CLOSPI_01136 | Hypothetical protein; KEGG: sbo:SBO_2558 0.0059 putative enzyme; COG: COG1073 Hydrolases of the alpha/beta superfamily. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.416 |
| EDS75284.1 | EDS75287.1 | CLOSPI_01135 | CLOSPI_01138 | Nucleic acid-binding domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.815 |
| EDS75284.1 | mprF | CLOSPI_01135 | CLOSPI_01137 | Nucleic acid-binding domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.823 |
| EDS75284.1 | recX | CLOSPI_01135 | CLOSPI_01136 | Nucleic acid-binding domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.826 |
| EDS75287.1 | EDS74547.1 | CLOSPI_01138 | CLOSPI_01602 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: sbo:SBO_2558 0.0059 putative enzyme; COG: COG1073 Hydrolases of the alpha/beta superfamily. | 0.411 |
| EDS75287.1 | EDS75284.1 | CLOSPI_01138 | CLOSPI_01135 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Nucleic acid-binding domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. | 0.815 |
| EDS75287.1 | EDS75344.1 | CLOSPI_01138 | CLOSPI_00738 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | SNARE-like domain protein; KEGG: pat:Patl_3732 0.0074 phospholipase D K01115; COG: COG0398 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.613 |
| EDS75287.1 | glgB | CLOSPI_01138 | CLOSPI_00081 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | 0.594 |
| EDS75287.1 | glgP | CLOSPI_01138 | CLOSPI_00080 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | 0.457 |
| EDS75287.1 | mprF | CLOSPI_01138 | CLOSPI_01137 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.846 |
| EDS75287.1 | recX | CLOSPI_01138 | CLOSPI_01136 | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.986 |
| EDS75344.1 | EDS75287.1 | CLOSPI_00738 | CLOSPI_01138 | SNARE-like domain protein; KEGG: pat:Patl_3732 0.0074 phospholipase D K01115; COG: COG0398 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99. | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.613 |
| glgB | EDS75287.1 | CLOSPI_00081 | CLOSPI_01138 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.594 |
| glgB | glgP | CLOSPI_00081 | CLOSPI_00080 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | 0.999 |
| glgB | recX | CLOSPI_00081 | CLOSPI_01136 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.656 |
| glgP | EDS75287.1 | CLOSPI_00080 | CLOSPI_01138 | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | Glycosyltransferase, group 1 family protein; KEGG: lsa:LSA1206 1.3e-88 putative glycosyl transferase, group 1 K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.457 |
| glgP | glgB | CLOSPI_00080 | CLOSPI_00081 | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | 0.999 |
| glgP | recX | CLOSPI_00080 | CLOSPI_01136 | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.477 |
| mprF | EDS75284.1 | CLOSPI_01137 | CLOSPI_01135 | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | Nucleic acid-binding domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. | 0.823 |