STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asnAAspartate--ammonia ligase; KEGG: lsl:LSL_1033 8.2e-137 asnA; aspartate--ammonia ligase K01914; COG: COG2502 Asparagine synthetase A; Psort location: Cytoplasmic, score: 10.00. (335 aa)    
Predicted Functional Partners:
asnB-2
Asparagine synthase (glutamine-hydrolyzing); KEGG: lla:L00396 6.2e-155 asnB; asparagine synthetase B K01953; COG: COG0367 Asparagine synthase (glutamine-hydrolyzing); Psort location: Cytoplasmic, score: 8.87.
   
 
 0.868
asnB
KEGG: bsu:BG12240 2.5e-142 asnO, yisO, yucB; asparagine synthase K01953; COG: COG0367 Asparagine synthase (glutamine-hydrolyzing); Psort location: Cytoplasmic, score: 8.87.
   
 
 0.866
argG
KEGG: lma:LmjF23.0260 2.3e-132 argininosuccinate synthase, putative K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
  0.849
pyrB
KEGG: bat:BAS3740 3.5e-81 aspartate carbamoyltransferase K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.65; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
 0.849
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.849
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
  0.632
EDS75697.1
KEGG: aae:aq_1812 4.4e-67 thrA; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
   
 
  0.599
EDS74843.1
Hypothetical protein; KEGG: ctc:CTC01982 0.0016 L-serine dehydratase alpha subunit K01752; COG: COG3681 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 9.98; Belongs to the UPF0597 family.
       0.527
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.482
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.482
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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