STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74843.1Hypothetical protein; KEGG: ctc:CTC01982 0.0016 L-serine dehydratase alpha subunit K01752; COG: COG3681 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 9.98; Belongs to the UPF0597 family. (422 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
       0.701
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.701
EDS74846.1
Oxidoreductase; COG: NOG16874 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.623
EDS75473.1
KEGG: bth:BT4678 3.0e-100 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87.
 
  
  0.571
asnA
Aspartate--ammonia ligase; KEGG: lsl:LSL_1033 8.2e-137 asnA; aspartate--ammonia ligase K01914; COG: COG2502 Asparagine synthetase A; Psort location: Cytoplasmic, score: 10.00.
       0.527
EDS73770.1
Phosphodiesterase family protein; KEGG: eci:UTI89_C2584 3.5e-42 yfcE; hypothetical protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.
  
     0.467
EDS73865.1
Hypothetical protein; COG: COG0716 Flavodoxins.
 
     0.453
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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