STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (408 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
   
  0.954
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
    
 0.921
EDS74665.1
Glutamine synthetase, beta-grasp domain protein; KEGG: mma:MM0964 3.0e-91 glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
    
 0.873
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.872
EDS75221.1
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: fth:FTH_0268 4.7e-157 glutamate dehydrogenase (NADP(+)) K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score: 9.98; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.864
EDS74839.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.827
EDS75818.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: syn:sll1027 1.8e-132 gltD; NADH-dependent glutamate synthase small subunit K00269; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
    
 0.801
gltA
KEGG: chy:CHY_1991 3.5e-161 gltA; glutamate synthase (NADPH), homotetrameric K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
    
 0.801
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.744
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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