STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimPHypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (155 aa)    
Predicted Functional Partners:
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.965
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
  
  
 0.959
EDS74893.1
COG: COG1358 Ribosomal protein HS6-type (S12/L30/L7a).
 
  
 0.956
EDS74892.1
Hypothetical protein; COG: COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.954
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
 
 0.952
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
  
 0.943
rpsB
COG: COG0052 Ribosomal protein S2; Psort location: Cytoplasmic, score: 8.87; Belongs to the universal ribosomal protein uS2 family.
  
   0.875
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
 
 0.873
rpsP
COG: COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
   0.861
EDS73854.1
KEGG: sha:SH2518 7.6e-47 ksgA; putative dimethyladenosine transferase K02528; COG: COG0030 Dimethyladenosine transferase (rRNA methylation); Psort location: Cytoplasmic, score: 8.87.
    
 
 0.852
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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