STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74900.1Reverse transcriptase (RNA-dependent DNA polymerase); KEGG: pol:Bpro_5394 2.2e-79 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87. (472 aa)    
Predicted Functional Partners:
EDS74901.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.475
EDS74902.1
Pseudouridylate synthase; KEGG: tte:TTE0052 1.1e-61 rsuA; 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase K06183; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
       0.475
EDS74899.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.442
cas2
CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
   0.427
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
   0.427
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.417
EDS74904.1
Thioredoxin; KEGG: hpa:HPAG1_1457 8.6e-07 thioredoxin K05905; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 8.87.
       0.417
EDS74905.1
tRNA binding domain protein; KEGG: sab:SAB1602c 8.1e-43 phenylalanyl-tRNA synthetase beta subunit; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98.
       0.407
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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