STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74911.1Reverse transcriptase (RNA-dependent DNA polymerase); KEGG: pol:Bpro_5394 2.2e-79 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87. (472 aa)    
Predicted Functional Partners:
EDS74912.1
Peptidase M16 inactive domain protein; KEGG: bld:BLi01909 1.6e-67 hypothetical protein; COG: COG0612 Predicted Zn-dependent peptidases; Psort location: Cytoplasmic, score: 8.87.
     
 0.468
EDS74913.1
Peptidase M16 inactive domain protein; KEGG: bcz:BCZK3546 1.1e-104 insulysin, peptidase family M16 (insulinase) K01408; COG: COG0612 Predicted Zn-dependent peptidases; Psort location: Cytoplasmic, score: 8.87.
       0.468
EDS74910.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.442
cas2
CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
   0.427
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
   0.427
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.