STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydGIron-only hydrogenase maturation rSAM protein HydG; KEGG: mac:MA0154 2.8e-16 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.87. (475 aa)    
Predicted Functional Partners:
hydF
Hydrogenase maturation GTPase HydF; KEGG: hpa:HPAG1_0820 4.1e-11 GTP-binding protein-like protein K00058; COG: COG1160 Predicted GTPases; Psort location: Cytoplasmic, score: 8.87.
  
 0.987
EDS74990.1
Putative iron-only hydrogenase system regulator; COG: NOG17852 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.917
hydE
Iron-only hydrogenase maturation rSAM protein HydE; KEGG: bth:BT1835 5.6e-106 biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
 
  
0.831
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.808
EDS74444.1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 1.4e-180 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.783
spoIIAB
Anti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
   
    0.693
EDS74451.1
Hypothetical protein; KEGG: fal:FRAAL1277 1.4e-06 serine/threonine-protein kinase (switch protein/serine kinase) (anti-sigma B factor RsbT) K08282; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
   
    0.693
purC
KEGG: tte:TTE0588 2.8e-72 purC; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the SAICAR synthetase family.
    
 0.641
EDS74574.1
FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87.
    
  0.631
EDS74371.1
Hypothetical protein; KEGG: lic:LIC13172 3.7e-07 adenosine deaminase K01489; COG: NOG34388 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
    
  0.592
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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