STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74990.1Putative iron-only hydrogenase system regulator; COG: NOG17852 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (81 aa)    
Predicted Functional Partners:
hydE
Iron-only hydrogenase maturation rSAM protein HydE; KEGG: bth:BT1835 5.6e-106 biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.943
hydF
Hydrogenase maturation GTPase HydF; KEGG: hpa:HPAG1_0820 4.1e-11 GTP-binding protein-like protein K00058; COG: COG1160 Predicted GTPases; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.936
hydG
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: mac:MA0154 2.8e-16 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.917
EDS75671.1
Iron chelate uptake ABC transporter, FeCT family, permease protein; KEGG: bxe:Bxe_A4149 0.0022 cytochrome bd ubiquinol oxidase, subunit II K00426; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
 0.912
EDS74645.1
Iron chelate uptake ABC transporter, FeCT family, permease protein; COG: COG0609 ABC-type Fe3+-siderophore transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
 0.912
EDS75668.1
Iron transport-associated domain protein; COG: COG5386 Cell surface protein.
  
 0.840
isdE
Heme ABC transporter, heme-binding protein isdE; COG: COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.
  
 0.840
EDS74646.1
Periplasmic binding protein; COG: COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.
  
 0.840
pdxB
KEGG: cac:CAC1543 2.3e-93 lactate dehydrogenase K03778; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.478
EDS74986.1
Ser/Thr phosphatase family protein; KEGG: bcz:BCZK1892 4.4e-58 possible serine/threonine specific protein phosphatase K01090; COG: COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; Psort location: Cytoplasmic, score: 8.87.
       0.469
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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