STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75021.1Conserved hypothetical protein TIGR03982; COG: COG2323 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 7.63. (232 aa)    
Predicted Functional Partners:
spoVAD
Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group.
 
  
 0.779
spoVAC
Stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
 
  
 0.763
EDS74431.1
Putative stage V sporulation protein AE; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.736
spoIVA
Stage IV sporulation protein A; KEGG: cno:NT01CX_0264 0.0018 hemA; glutamyl-tRNA reductase K00155; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.715
EDS74947.1
Putative SpoIVB peptidase; KEGG: btl:BALH_3781 6.9e-53 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.
  
    0.709
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
     0.653
EDS73961.1
Putative sporulation transcription factor Spo0A; KEGG: ava:Ava_B0029 7.3e-05 two component transcriptional regulator, LuxR family; COG: COG0784 FOG: CheY-like receiver.
  
     0.628
EDS73819.1
KEGG: oih:OB0074 1.3e-40 stage II sporulation protein E K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.617
EDS73960.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
     0.613
EDS75022.1
COG: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
       0.612
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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