STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS75028.1Hypothetical protein; KEGG: lsl:LSL_1510 5.2e-16 pncA; pyrazinamidase / nicotinamidase K01463:K01440; COG: COG1335 Amidases related to nicotinamidase. (172 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 
 0.905
deoD
KEGG: ssp:SSP0746 6.7e-71 purine nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase.
    
  0.842
EDS75022.1
COG: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
  
 
 0.696
EDS75995.1
Transcriptional regulator, Sir2 family; KEGG: tte:TTE1570 7.9e-13 sir2; NAD-dependent protein deacetylase, Sir2 family K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: Cytoplasmic, score: 8.87.
  
 0.670
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.649
EDS75482.1
Putative endoribonuclease L-PSP; KEGG: ape:APE_1501.1 1.6e-23 ribonuclease UK114; COG: COG0251 Putative translation initiation inhibitor, yjgF family.
  
 
 0.647
gatA
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
    
 0.628
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.618
EDS75027.1
Metallo-beta-lactamase domain protein; KEGG: afu:AF0939 2.2e-07 ribonuclease Z K00784; COG: COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; Psort location: Cytoplasmic, score: 8.87.
 
     0.604
EDS74641.1
2Fe-2S iron-sulfur cluster-binding domain protein; KEGG: mag:amb2019 7.9e-29 4-hydroxybenzoyl-CoA reductase gamma subunit K04107; COG: COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.601
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.