STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheSKEGG: bld:BLi03016 1.4e-123 pheS; phenylalanyl-tRNA synthetase (alpha subunit); RBL00343 K01889; COG: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Psort location: Cytoplasmic, score: 10.00. (373 aa)    
Predicted Functional Partners:
pheT
KEGG: gka:GK2706 2.5e-151 phenylalanyl-tRNA synthetase beta subunit K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98.
 
 0.999
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.985
EDS74905.1
tRNA binding domain protein; KEGG: sab:SAB1602c 8.1e-43 phenylalanyl-tRNA synthetase beta subunit; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98.
 
 0.971
serS
serine--tRNA ligase; KEGG: mhu:Mhun_2507 1.1e-86 seryl-tRNA synthetase K01875; COG: COG0172 Seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
   
 
 0.721
rplP
Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
  
 0.711
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.669
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.658
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
  
 0.656
thrS
threonine--tRNA ligase; KEGG: fnu:FN0611 1.7e-182 threonyl-tRNA synthetase K01868; COG: COG0441 Threonyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.654
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.649
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.