STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmcALHypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (379 aa)    
Predicted Functional Partners:
EDS74788.1
Hypothetical protein; COG: COG3610 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.775
EDS74789.1
Hypothetical protein; COG: COG2966 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.775
EDS73968.1
Methyltransferase small domain protein; KEGG: mmy:MSC_0044 4.3e-60 methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the methyltransferase superfamily.
 
     0.746
EDS73826.1
DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.724
polC
DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
    0.682
EDS74544.1
COG: COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.592
EDS74790.1
Hypothetical protein; KEGG: dps:DP0920 1.0e-12 probable methylated-DNA-protein-cysteine methyltransferase K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase.
       0.522
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
   
 0.452
ecfA-2
ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
     0.442
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
     0.406
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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