Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
spoIVAStage IV sporulation protein A; KEGG: cno:NT01CX_0264 0.0018 hemA; glutamyl-tRNA reductase K00155; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (491 aa)    
Predicted Functional Partners:
spoIID
COG: COG2385 Sporulation protein and related proteins.
  
  
 0.889
spoIIP
Stage II sporulation protein P; COG: NOG06343 non supervised orthologous group.
 
   
 0.856
spoIIAB
Anti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
  
  
 0.818
EDS74197.1
Hypothetical protein; COG: COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis; Psort location: CytoplasmicMembrane, score: 9.99.
  
   
 0.814
EDS73819.1
KEGG: oih:OB0074 1.3e-40 stage II sporulation protein E K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: CytoplasmicMembrane, score: 9.99.
  
   
 0.814
cotE
Spore coat protein E; COG: NOG09743 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.811
EDS75788.1
Peptidase, M23 family; KEGG: bas:BUsg310 1.6e-06 yebA; hypothetical 46.7 kD protein in msbB-ruvB; COG: COG0739 Membrane proteins related to metalloendopeptidases.
  
  
 0.802
gpr
KEGG: bli:BL02089 5.7e-42 gpr; spore protease K06012; COG: NOG08575 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.801
spoVAC
Stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
   
 0.801
EDS73960.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.801
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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