STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupDNA-binding protein HU; KEGG: pub:SAR11_0607 0.00046 sfhB; pseudouridylate synthase K06180; COG: COG0776 Bacterial nucleoid DNA-binding protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the bacterial histone-like protein family. (103 aa)    
Predicted Functional Partners:
spoIVA
Stage IV sporulation protein A; KEGG: cno:NT01CX_0264 0.0018 hemA; glutamyl-tRNA reductase K00155; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.700
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.608
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  
 0.583
EDS74797.1
Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99.
       0.558
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
 
   0.547
EDS75141.1
KEGG: efa:EF1922 0.00014 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.533
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.529
EDS74218.1
Chorismate mutase; KEGG: aae:aq_951 3.3e-53 pheA; chorismate mutase/prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
     
 0.512
cas1
CRISPR-associated endonuclease Cas1, NMENI subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
    
   0.509
cas1-2
CRISPR-associated endonuclease Cas1, HMARI/TNEAP subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
    
   0.509
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.