STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74797.1Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99. (235 aa)    
Predicted Functional Partners:
hup
DNA-binding protein HU; KEGG: pub:SAR11_0607 0.00046 sfhB; pseudouridylate synthase K06180; COG: COG0776 Bacterial nucleoid DNA-binding protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the bacterial histone-like protein family.
       0.558
spoIVA
Stage IV sporulation protein A; KEGG: cno:NT01CX_0264 0.0018 hemA; glutamyl-tRNA reductase K00155; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.528
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.487
EDS74799.1
DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.482
EDS74798.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.449
spoVS
COG: COG2359 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
     0.411
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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