| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS74797.1 | EDS74798.1 | CLOSPI_01381 | CLOSPI_01382 | Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 0.449 |
| EDS74797.1 | EDS74799.1 | CLOSPI_01381 | CLOSPI_01383 | Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99. | DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.474 |
| EDS74797.1 | nth | CLOSPI_01381 | CLOSPI_01384 | Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.474 |
| EDS74798.1 | EDS74797.1 | CLOSPI_01382 | CLOSPI_01381 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99. | 0.449 |
| EDS74798.1 | EDS74799.1 | CLOSPI_01382 | CLOSPI_01383 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.775 |
| EDS74798.1 | nth | CLOSPI_01382 | CLOSPI_01384 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.775 |
| EDS74799.1 | EDS74797.1 | CLOSPI_01383 | CLOSPI_01381 | DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87. | Putative neutral zinc metallopeptidase; COG: COG2738 Predicted Zn-dependent protease; Psort location: CytoplasmicMembrane, score: 9.99. | 0.474 |
| EDS74799.1 | EDS74798.1 | CLOSPI_01383 | CLOSPI_01382 | DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. | 0.775 |
| EDS74799.1 | nth | CLOSPI_01383 | CLOSPI_01384 | DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.944 |
| metG | mutL | CLOSPI_02389 | CLOSPI_01406 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.441 |
| metG | nth | CLOSPI_02389 | CLOSPI_01384 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.576 |
| metG | polA | CLOSPI_02389 | CLOSPI_00138 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.736 |
| metG | xth | CLOSPI_02389 | CLOSPI_00022 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Exodeoxyribonuclease III; KEGG: cac:CAC0222 1.2e-96 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score: 9.98. | 0.560 |
| mutL | metG | CLOSPI_01406 | CLOSPI_02389 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.441 |
| mutL | nth | CLOSPI_01406 | CLOSPI_01384 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.655 |
| mutL | polA | CLOSPI_01406 | CLOSPI_00138 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.967 |
| mutL | recJ | CLOSPI_01406 | CLOSPI_00978 | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | KEGG: ser:SERP1199 1.7e-81 recJ; single-stranded-DNA-specific exonuclease RecJ; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.87. | 0.603 |
| nfo | nth | CLOSPI_01871 | CLOSPI_01384 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.875 |
| nfo | polA | CLOSPI_01871 | CLOSPI_00138 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.615 |
| nfo | recJ | CLOSPI_01871 | CLOSPI_00978 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | KEGG: ser:SERP1199 1.7e-81 recJ; single-stranded-DNA-specific exonuclease RecJ; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.87. | 0.611 |
