STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnyYmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (518 aa)    
Predicted Functional Partners:
EDS73969.1
PSP1 C-terminal domain protein; COG: COG1774 Uncharacterized homolog of PSP1; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.762
EDS74814.1
Putative metallophosphoesterase; COG: COG1692 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.710
spoVS
COG: COG2359 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.539
EDS75148.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
 0.476
EDS73872.1
tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: tdn:Tmden_0005 4.2e-46 polynucleotide adenylyltransferase region K00974; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.469
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.435
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
  0.416
EDS75122.1
DHHA1 domain protein; KEGG: stl:stu0372 1.6e-06 ppaC; manganese-dependent inorganic pyrophosphatase K01507; COG: COG0618 Exopolyphosphatase-related proteins; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.408
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
    0.404
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.