STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVSCOG: COG2359 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (86 aa)    
Predicted Functional Partners:
EDS74814.1
Putative metallophosphoesterase; COG: COG1692 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
    0.680
rny
YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
       0.538
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.523
EDS74817.1
Hypothetical protein; KEGG: pub:SAR11_0505 0.0052 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0342 family.
       0.453
EDS74309.1
STAS domain protein; KEGG: msu:MS1346 0.0064 hemH; protoheme ferro-lyase (ferrochelatase) K01772; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
  
 0.449
yabP
Sporulation protein YabP; COG: NOG13819 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.444
EDS73960.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.444
EDS73961.1
Putative sporulation transcription factor Spo0A; KEGG: ava:Ava_B0029 7.3e-05 two component transcriptional regulator, LuxR family; COG: COG0784 FOG: CheY-like receiver.
  
  
 0.444
cotE
Spore coat protein E; COG: NOG09743 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.428
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
      
 0.425
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.