STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74705.1Hypothetical protein; KEGG: hit:NTHI1634 2.3e-14 NAD-dependent deacetylase sirtuin 5 K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family. (298 aa)    
Predicted Functional Partners:
EDS74706.1
Macro domain protein; KEGG: bur:Bcep18194_A6181 7.7e-22 Appr-1-p processing enzyme family K00985; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87.
  
 0.993
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.917
EDS75221.1
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: fth:FTH_0268 4.7e-157 glutamate dehydrogenase (NADP(+)) K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score: 9.98; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.892
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.875
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.567
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.567
EDS74707.1
Hypothetical protein.
       0.566
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 0.561
EDS75028.1
Hypothetical protein; KEGG: lsl:LSL_1510 5.2e-16 pncA; pyrazinamidase / nicotinamidase K01463:K01440; COG: COG1335 Amidases related to nicotinamidase.
  
 0.536
EDS76027.1
Oxidoreductase, NAD-binding domain protein; KEGG: hsa:27294 3.1e-27 DHDH; dihydrodiol dehydrogenase (dimeric) K00212; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87.
   
  0.533
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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