STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS74706.1Macro domain protein; KEGG: bur:Bcep18194_A6181 7.7e-22 Appr-1-p processing enzyme family K00985; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87. (253 aa)    
Predicted Functional Partners:
EDS74705.1
Hypothetical protein; KEGG: hit:NTHI1634 2.3e-14 NAD-dependent deacetylase sirtuin 5 K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family.
 
  0.993
EDS76053.1
Macro domain protein; KEGG: reh:H16_A1552 2.6e-30 predicted phosphatase homolog to the C-terminal domain of histone macroH2A1; COG: COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1; Psort location: Cytoplasmic, score: 8.87.
 
    
0.728
rplX
Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.642
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.636
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
   0.578
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.577
EDS76059.1
Putative permease; KEGG: bcz:BCZK0244 4.3e-115 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: CytoplasmicMembrane, score: 9.99.
      0.571
EDS74707.1
Hypothetical protein.
       0.566
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
   0.511
EDS74704.1
YbaK/proline--tRNA ligase associated domain protein; KEGG: bli:BL01235 2.9e-08 proS; prolyl-tRNA synthetase K01881; COG: COG2606 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.509
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.