STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74734.1IstB-like ATP-binding protein; COG: COG1484 DNA replication protein. (140 aa)    
Predicted Functional Partners:
EDS75450.1
Integrase core domain protein; COG: COG4584 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.782
EDS75455.1
IstB-like ATP-binding protein; KEGG: spi:MGAS10750_Spy1680 0.0015 replicative DNA helicase K01529; COG: COG1484 DNA replication protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.775
EDS74735.1
Hypothetical protein; COG: COG3666 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.773
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.697
EDS74733.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 1.6e-12 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase.
       0.568
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.405
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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