STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdMKEGG: spa:M6_Spy1631 5.8e-159 type I restriction-modification system methylation subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87. (546 aa)    
Predicted Functional Partners:
EDS74752.1
KEGG: blo:BL1783 3.1e-41 hsdS; HsdS specificity protein of type I restriction-modification system K01154; COG: NOG32801 non supervised orthologous group.
 
 
 0.995
hsdR
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 0.992
EDS74751.1
Type I restriction modification DNA specificity domain protein; KEGG: yps:YPTB0536 1.3e-58 putative type I restriction enzyme, S subunit K01154; COG: COG0732 Restriction endonuclease S subunits.
 
 0.987
EDS74749.1
Site-specific recombinase, phage integrase family; COG: COG0582 Integrase; Psort location: Cytoplasmic, score: 8.87; Belongs to the 'phage' integrase family.
 
   
 0.799
EDS74754.1
Hypothetical protein.
       0.773
EDS74766.1
Hypothetical protein; KEGG: gka:GK0346 1.0e-14 type I restriction-modification system R subunit (endonuclease) K01153; COG: COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.608
EDS74767.1
Hypothetical protein; KEGG: gka:GK0346 2.0e-08 type I restriction-modification system R subunit (endonuclease) K01153; COG: COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
  
 
 0.608
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.557
FbpA
Fibronectin-binding protein A domain protein; KEGG: fnu:FN0522 1.5e-05 exonuclease SBCC K03546; COG: COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; Psort location: Cytoplasmic, score: 8.87.
  
    0.413
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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