Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDS74777.1Hypothetical protein; KEGG: pol:Bpro_5394 6.6e-48 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87. (268 aa)    
Predicted Functional Partners:
EDS76132.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 8.3e-26 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87.
 
      0.883
EDS75304.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 8.3e-26 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87.
 
      0.883
EDS74562.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 8.3e-26 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87.
 
      0.883
EDS75477.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 7.3e-19 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase.
 
      0.724
cas1-2
CRISPR-associated endonuclease Cas1, HMARI/TNEAP subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
      0.670
EDS75762.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 1.6e-12 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase.
 
      0.624
EDS74733.1
Group II intron, maturase-specific domain protein; KEGG: pol:Bpro_5394 1.6e-12 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase.
 
      0.624
EDS74778.1
Transposase; COG: COG2963 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.527
EDS74779.1
Integrase core domain protein; KEGG: nwi:Nwi_0782 6.9e-09 integrase, catalytic region K00986; COG: COG2801 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.496
EDS74776.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.442
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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