STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74782.1Hypothetical protein; KEGG: stl:stu0711 1.8e-32 hsdM1; type I restriction-modification system methyltransferase subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87. (167 aa)    
Predicted Functional Partners:
EDS74751.1
Type I restriction modification DNA specificity domain protein; KEGG: yps:YPTB0536 1.3e-58 putative type I restriction enzyme, S subunit K01154; COG: COG0732 Restriction endonuclease S subunits.
 
 
 0.978
EDS74752.1
KEGG: blo:BL1783 3.1e-41 hsdS; HsdS specificity protein of type I restriction-modification system K01154; COG: NOG32801 non supervised orthologous group.
 
 
 0.978
hsdR
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.928
EDS74781.1
Hypothetical protein.
       0.773
EDS74749.1
Site-specific recombinase, phage integrase family; COG: COG0582 Integrase; Psort location: Cytoplasmic, score: 8.87; Belongs to the 'phage' integrase family.
 
   
 0.744
EDS74766.1
Hypothetical protein; KEGG: gka:GK0346 1.0e-14 type I restriction-modification system R subunit (endonuclease) K01153; COG: COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.630
EDS74767.1
Hypothetical protein; KEGG: gka:GK0346 2.0e-08 type I restriction-modification system R subunit (endonuclease) K01153; COG: COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
  
 
 0.630
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.481
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.467
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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