STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74578.1KEGG: sak:SAK_0393 9.4e-18 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. (262 aa)    
Predicted Functional Partners:
EDS74579.1
LytTr DNA-binding domain protein; COG: COG3279 Response regulator of the LytR/AlgR family.
       0.768
EDS75871.1
Cof-like hydrolase; KEGG: sec:SC0837 9.6e-40 ybiV(1); putative hydrolase of the HAD superfamily K07757; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
  
     0.751
EDS74601.1
KEGG: bcz:BCZK5094 4.5e-33 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
  
     0.750
EDS74600.1
Cof-like hydrolase; KEGG: btl:BALH_4896 6.8e-30 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
  
     0.732
EDS73980.1
Cof-like hydrolase; KEGG: btl:BALH_4896 9.6e-12 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily.
  
     0.728
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
       0.657
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
       0.655
EDS74580.1
ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 4.6e-72 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
  
 
  0.590
queH
Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
       0.543
gltA
KEGG: chy:CHY_1991 3.5e-161 gltA; glutamate synthase (NADPH), homotetrameric K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
       0.521
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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