STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74579.1LytTr DNA-binding domain protein; COG: COG3279 Response regulator of the LytR/AlgR family. (229 aa)    
Predicted Functional Partners:
EDS74015.1
Hypothetical protein; KEGG: sep:SE1637 6.6e-15 accessory gene regulator C K07706; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.798
EDS74578.1
KEGG: sak:SAK_0393 9.4e-18 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
       0.768
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
       0.650
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
       0.650
EDS75747.1
Hypothetical protein; COG: NOG14245 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
  
     0.615
EDS74014.1
LytTr DNA-binding domain protein; KEGG: wbr:WGLp088 0.0013 rne; ribonucleases G and E; COG: COG3279 Response regulator of the LytR/AlgR family; Psort location: Cytoplasmic, score: 9.98.
  
     0.580
queH
Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
       0.539
EDS74580.1
ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 4.6e-72 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
       0.524
gltA
KEGG: chy:CHY_1991 3.5e-161 gltA; glutamate synthase (NADPH), homotetrameric K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
       0.524
EDS75465.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01848 1.4e-34 yesM; two-component sensor kinase YesM K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
  
 
 0.523
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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