STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74588.1DHHA2 domain protein; KEGG: cpe:CPE2055 1.0e-152 probable manganase-dependent inorganic pyrophosphatase K01507; COG: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; Psort location: Cytoplasmic, score: 8.87. (546 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.978
atpB-2
ATP synthase, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
  
 
 0.922
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.917
EDS74818.1
KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.915
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
    
 0.896
EDS75840.1
Putative calcium-translocating P-type ATPase, PMCA-type; KEGG: cpe:CPE0333 3.0e-226 probable cation-transporting ATPase K01529; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.883
EDS75879.1
E1-E2 ATPase; KEGG: smu:SMU.1563 3.5e-113 pacL; putative cation-transporting P-type ATPase PacL K01529; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.883
EDS75880.1
Haloacid dehalogenase-like hydrolase; KEGG: smu:SMU.1563 5.0e-169 pacL; putative cation-transporting P-type ATPase PacL K01529; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 9.99.
    
  0.883
EDS75577.1
E1-E2 ATPase; KEGG: efa:EF1519 1.2e-153 cation-transporting ATPase, E1-E2 family; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.883
EDS75110.1
Putative calcium-translocating P-type ATPase, PMCA-type; KEGG: cpe:CPE0333 3.2e-286 probable cation-transporting ATPase K01529; COG: COG0474 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.883
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.