STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74589.1S4 domain protein; KEGG: tma:TM0462 1.2e-06 conserved hypothetical protein K06180; COG: COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog). (88 aa)    
Predicted Functional Partners:
FbpA
Fibronectin-binding protein A domain protein; KEGG: fnu:FN0522 1.5e-05 exonuclease SBCC K03546; COG: COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; Psort location: Cytoplasmic, score: 8.87.
  
 
 
 0.918
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.883
hslO
Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
  
 0.845
rplQ
COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.843
rpmB
COG: COG0227 Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.838
rpmH
COG: COG0230 Ribosomal protein L34; Psort location: Extracellular, score: 8.82; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.834
rpmA
COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.830
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.830
rplT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.829
rpmF
COG: COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
    
   0.825
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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