STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folCBifunctional protein FolC; KEGG: bca:BCE_4548 8.8e-53 folC; folylpolyglutamate synthase K01930; COG: COG0285 Folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 8.87. (386 aa)    
Predicted Functional Partners:
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
   0.804
EDS74600.1
Cof-like hydrolase; KEGG: btl:BALH_4896 6.8e-30 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
     
 0.777
EDS74601.1
KEGG: bcz:BCZK5094 4.5e-33 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87.
     
 0.776
EDS74604.1
KEGG: bca:BCE_3757 6.4e-34 acetyltransferase, GNAT family, putative K03830; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
       0.758
EDS74605.1
Hypothetical protein.
       0.757
EDS74599.1
KEGG: pfu:PF1108 9.4e-33 putative alpha-dextrin endo-1,6-alpha-glucosidase K01200; COG: COG2819 Predicted hydrolase of the alpha/beta superfamily; Psort location: Cytoplasmic, score: 8.87.
       0.748
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
     0.662
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.616
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
   
 0.516
EDS74598.1
COG: COG2919 Septum formation initiator; Psort location: Cytoplasmic, score: 8.87.
       0.513
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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