STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ptsPPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (576 aa)    
Predicted Functional Partners:
EDS76125.1
Phosphocarrier, HPr family; KEGG: btl:BALH_3665 3.0e-20 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 10.00.
 
 0.998
ptsH
Phosphocarrier protein HPr; KEGG: btl:BALH_3665 4.8e-13 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 10.00.
 
 0.993
EDS75802.1
KEGG: lmf:LMOf2365_0442 1.4e-20 PTS system, fructose-specific, IIA component K02768; COG: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); Psort location: Cytoplasmic, score: 8.87.
  
 0.985
EDS73779.1
KEGG: sar:SAR0235 1.9e-137 putative PTS transport system, IIBC component K02790:K02791; COG: COG1264 Phosphotransferase system IIB components; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.971
EDS75491.1
Hypothetical protein; KEGG: sha:SH0521 2.0e-10 ptsG; phosphotransferase system enzyme II K02777:K02778:K02779; COG: COG2190 Phosphotransferase system IIA components.
 
 
 0.958
ptbA
KEGG: cac:CAC1354 1.4e-24 PTS system, N-acetylglucosamine-specific IIA component, putative K02802; COG: COG2190 Phosphotransferase system IIA components; Psort location: Cytoplasmic, score: 9.65.
 
 
 0.927
EDS75580.1
KEGG: cpr:CPR_0550 6.2e-171 fructose specific permease K00890; COG: COG1299 Phosphotransferase system, fructose-specific IIC component; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.832
nagE
KEGG: sgl:SG0859 6.9e-140 PTS system N-acetylglucosamine-specific IIABC component K02802:K02803:K02804; COG: COG2190 Phosphotransferase system IIA components; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.775
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
 
   
 0.710
EDS75141.1
KEGG: efa:EF1922 0.00014 transcriptional regulator, LacI family/carbohydrate kinase, PfkB family protein K00852; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.622
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.