STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74115.1Putative dGTPase; KEGG: pcu:pc0465 4.6e-47 dgt; putative deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) K01129; COG: COG0232 dGTP triphosphohydrolase; Psort location: Cytoplasmic, score: 8.87. (414 aa)    
Predicted Functional Partners:
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
    
  0.849
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
       0.648
EDS73772.1
KEGG: tbr:Tb927.7.5790 0.0013 protein disulfide isomerase K01829; Psort location: Cytoplasmic, score: 8.87.
    
  0.610
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.602
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
       0.554
EDS74408.1
Hypothetical protein; KEGG: ctc:CTC02272 5.5e-28 purine nucleoside phosphorylase K00755; COG: COG1683 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
    
  0.532
EDS75425.1
Hypothetical protein; KEGG: tma:TM1254 2.9e-11 beta-phosphoglucomutase, putative K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: CytoplasmicMembrane, score: 9.26.
 
  
  0.506
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.447
mtnN-2
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.447
EDS75230.1
LysM domain protein; KEGG: aeh:Mlg_1995 5.1e-06 lytic transglycosylase, catalytic K08307; COG: COG3409 Putative peptidoglycan-binding domain-containing protein.
    
  0.442
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (24%) [HD]