STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (321 aa)    
Predicted Functional Partners:
EDS74130.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: gka:GK0284 6.0e-118 O-acetylhomoserine sulfhydrylase K01740; COG: COG2873 O-acetylhomoserine sulfhydrylase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.971
EDS75963.1
Amino acid kinase family; KEGG: cac:CAC0278 4.7e-125 aspartate kinase K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score: 8.87; Belongs to the aspartokinase family.
 
 
 0.943
EDS75697.1
KEGG: aae:aq_1812 4.4e-67 thrA; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.906
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.870
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
  0.850
EDS75473.1
KEGG: bth:BT4678 3.0e-100 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87.
     
 0.846
metF
KEGG: mxa:MXAN_3039 1.4e-61 metF; 5,10-methylenetetrahydrofolate reductase; COG: COG0685 5,10-methylenetetrahydrofolate reductase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.826
EDS75105.1
KEGG: ctc:CTC01806 2.7e-209 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.784
EDS75346.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: bce:BC0791 4.5e-136 NADH dehydrogenase K00359; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: Cytoplasmic, score: 9.65; Belongs to the sulfur carrier protein TusA family.
  
    0.749
EDS74090.1
Hypothetical protein; KEGG: ftl:FTL_0636 3.2e-09 NADH oxidase K00359; COG: COG0607 Rhodanese-related sulfurtransferase.
   
    0.721
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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