def protein (Clostridium spiroforme) - STRING interaction network

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def

Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (189 aa)

Predicted Functional Partners:

rplU

0.895

rplQ

0.892

rplV

0.881

nifJ

0.880

rpsT

0.872

rpsU

0.870

rpsF

0.863

rpmB

0.855

rpsP

0.855

rplD

0.855

Your Current Organism:

Clostridium spiroforme

NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def	nifJ	CLOSPI_01713	CLOSPI_00003	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.	0.880
def	rplD	CLOSPI_01713	CLOSPI_01570	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.855
def	rplQ	CLOSPI_01713	CLOSPI_01596	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score: 8.87.	0.892
def	rplU	CLOSPI_01713	CLOSPI_00884	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.895
def	rplV	CLOSPI_01713	CLOSPI_01574	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.881
def	rpmB	CLOSPI_01713	CLOSPI_00858	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	COG: COG0227 Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.855
def	rpsF	CLOSPI_01713	CLOSPI_02449	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.863
def	rpsP	CLOSPI_01713	CLOSPI_01183	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	COG: COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.855
def	rpsT	CLOSPI_01713	CLOSPI_01882	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.872
def	rpsU	CLOSPI_01713	CLOSPI_00110	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	COG: COG0828 Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.	0.870
nifJ	def	CLOSPI_00003	CLOSPI_01713	KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.880
rplD	def	CLOSPI_01570	CLOSPI_01713	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.855
rplD	rplQ	CLOSPI_01570	CLOSPI_01596	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score: 8.87.	0.993
rplD	rplU	CLOSPI_01570	CLOSPI_00884	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.988
rplD	rplV	CLOSPI_01570	CLOSPI_01574	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rplD	rpmB	CLOSPI_01570	CLOSPI_00858	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	COG: COG0227 Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.985
rplD	rpsF	CLOSPI_01570	CLOSPI_02449	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.987
rplD	rpsP	CLOSPI_01570	CLOSPI_01183	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	COG: COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.987
rplD	rpsT	CLOSPI_01570	CLOSPI_01882	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.974
rplD	rpsU	CLOSPI_01570	CLOSPI_00110	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	COG: COG0828 Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.	0.955

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