STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimIRibosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa)    
Predicted Functional Partners:
yeaZ
Universal bacterial protein YeaZ; KEGG: mcp:MCAP_0267 4.8e-22 metalloendopeptidase, putative; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.957
tsaD
Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
  
 0.947
EDS74173.1
Hydrolase, P-loop family; KEGG: cjk:jk1734 2.1e-14 alr; hypothetical protein K01775; COG: COG0802 Predicted ATPase or kinase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.880
rex
CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.813
EDS74172.1
Hypothetical protein; KEGG: mpu:MYPU_1770 3.6e-26 cysS; cysteinyl-tRNA synthetase K01883; COG: COG3557 Uncharacterized domain/protein associated with RNAses G and E; Psort location: Cytoplasmic, score: 8.87.
       0.771
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.704
asnS
asparagine--tRNA ligase; KEGG: ctc:CTC00143 9.4e-152 asparaginyl-tRNA synthetase K01893; COG: COG0017 Aspartyl/asparaginyl-tRNA synthetases; Psort location: Cytoplasmic, score: 10.00.
       0.647
EDS74171.1
Thiamine transporter protein (Thia_YuaJ); COG: COG3859 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.498
pdxB-2
KEGG: cff:CFF8240_1663 1.6e-67 hprA; glycerate dehydrogenase K00018; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.452
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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