STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDPutative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (344 aa)    
Predicted Functional Partners:
EDS74173.1
Hydrolase, P-loop family; KEGG: cjk:jk1734 2.1e-14 alr; hypothetical protein K01775; COG: COG0802 Predicted ATPase or kinase; Psort location: Cytoplasmic, score: 8.87.
 
 0.996
yeaZ
Universal bacterial protein YeaZ; KEGG: mcp:MCAP_0267 4.8e-22 metalloendopeptidase, putative; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.994
rimI
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
 
  
 0.947
rex
CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.794
EDS74172.1
Hypothetical protein; KEGG: mpu:MYPU_1770 3.6e-26 cysS; cysteinyl-tRNA synthetase K01883; COG: COG3557 Uncharacterized domain/protein associated with RNAses G and E; Psort location: Cytoplasmic, score: 8.87.
       0.771
asnS
asparagine--tRNA ligase; KEGG: ctc:CTC00143 9.4e-152 asparaginyl-tRNA synthetase K01893; COG: COG0017 Aspartyl/asparaginyl-tRNA synthetases; Psort location: Cytoplasmic, score: 10.00.
       0.631
gpsA
KEGG: bce:BC1505 5.7e-74 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057; COG: COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
      0.617
pheT
KEGG: gka:GK2706 2.5e-151 phenylalanyl-tRNA synthetase beta subunit K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.607
pheS
KEGG: bld:BLi03016 1.4e-123 pheS; phenylalanyl-tRNA synthetase (alpha subunit); RBL00343 K01889; COG: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Psort location: Cytoplasmic, score: 10.00.
 
   
 0.604
hflB
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
   
 0.595
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.