STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74206.1DNA-binding helix-turn-helix protein; KEGG: eba:ebA2762 0.00060 boxR; putative regulator of aerobic benzoate metabolic operon containing shikimate kinase-like domain K00891; COG: NOG36343 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (117 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.588
folA
KEGG: bli:BL03300 4.5e-26 dfrA; dihydrofolate reductase K00287; COG: COG0262 Dihydrofolate reductase; Psort location: Cytoplasmic, score: 8.87.
       0.580
EDS74209.1
Acyltransferase; KEGG: ctc:CTC00551 1.7e-26 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87.
       0.580
EDS74205.1
Hypothetical protein; KEGG: lla:L0022 0.0026 kdgA; 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase K01625:K01650; COG: NOG09943 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
    0.486
EDS75503.1
Hypothetical protein; COG: NOG35922 non supervised orthologous group.
  
     0.435
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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