| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS74119.1 | argC | CLOSPI_01701 | CLOSPI_00453 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.513 |
| EDS74119.1 | argD | CLOSPI_01701 | CLOSPI_01852 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87. | 0.921 |
| EDS74119.1 | argG | CLOSPI_01701 | CLOSPI_00448 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | KEGG: lma:LmjF23.0260 2.3e-132 argininosuccinate synthase, putative K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.564 |
| EDS74267.1 | argD | CLOSPI_01851 | CLOSPI_01852 | Amidohydrolase; KEGG: fnu:FN0590 4.7e-70 N-acyl-L-amino acid amidohydrolase K01436; COG: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; Psort location: Cytoplasmic, score: 8.87. | Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87. | 0.783 |
| EDS74267.1 | dapD | CLOSPI_01851 | CLOSPI_01850 | Amidohydrolase; KEGG: fnu:FN0590 4.7e-70 N-acyl-L-amino acid amidohydrolase K01436; COG: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; Psort location: Cytoplasmic, score: 8.87. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. | 0.918 |
| argB | argC | CLOSPI_00455 | CLOSPI_00453 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
| argB | argD | CLOSPI_00455 | CLOSPI_01852 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87. | 0.995 |
| argB | argF | CLOSPI_00455 | CLOSPI_00441 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.935 |
| argB | argG | CLOSPI_00455 | CLOSPI_00448 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | KEGG: lma:LmjF23.0260 2.3e-132 argininosuccinate synthase, putative K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.950 |
| argB | argH | CLOSPI_00455 | CLOSPI_00447 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Argininosuccinate lyase; KEGG: cpf:CPF_0682 2.5e-142 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score: 8.87. | 0.950 |
| argB | argJ | CLOSPI_00455 | CLOSPI_00454 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
| argC | EDS74119.1 | CLOSPI_00453 | CLOSPI_01701 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | 0.513 |
| argC | argB | CLOSPI_00453 | CLOSPI_00455 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
| argC | argD | CLOSPI_00453 | CLOSPI_01852 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87. | 0.995 |
| argC | argF | CLOSPI_00453 | CLOSPI_00441 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.919 |
| argC | argG | CLOSPI_00453 | CLOSPI_00448 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | KEGG: lma:LmjF23.0260 2.3e-132 argininosuccinate synthase, putative K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.961 |
| argC | argH | CLOSPI_00453 | CLOSPI_00447 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Argininosuccinate lyase; KEGG: cpf:CPF_0682 2.5e-142 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score: 8.87. | 0.957 |
| argC | argJ | CLOSPI_00453 | CLOSPI_00454 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.995 |
| argD | EDS74119.1 | CLOSPI_01852 | CLOSPI_01701 | Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87. | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. | 0.921 |
| argD | EDS74267.1 | CLOSPI_01852 | CLOSPI_01851 | Aminotransferase, acetylornithine/succinylornithine family; KEGG: mja:MJ0721 3.6e-95 argD; acetylornithine aminotransferase K00818; COG: COG4992 Ornithine/acetylornithine aminotransferase; Psort location: Cytoplasmic, score: 8.87. | Amidohydrolase; KEGG: fnu:FN0590 4.7e-70 N-acyl-L-amino acid amidohydrolase K01436; COG: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; Psort location: Cytoplasmic, score: 8.87. | 0.783 |