STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (583 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 0.994
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 0.991
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 
 0.957
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.918
EDS74282.1
Dinuclear metal center protein, YbgI family; COG: COG0327 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.833
glyS
glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.824
EDS74281.1
Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase.
       0.820
EDS76024.1
KEGG: btk:BT9727_4333 1.5e-215 dnaE; DNA polymerase III, alpha subunit K02337; COG: COG0587 DNA polymerase III, alpha subunit; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.721
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.695
hydF
Hydrogenase maturation GTPase HydF; KEGG: hpa:HPAG1_0820 4.1e-11 GTP-binding protein-like protein K00058; COG: COG1160 Predicted GTPases; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.695
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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