STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (415 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.995
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.964
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.961
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.946
bltR
Multidrug-efflux transporter 2 regulator; KEGG: eci:UTI89_C3737 0.00051 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG4978 Transcriptional regulator, effector-binding domain/component; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.860
EDS73678.1
Transcriptional regulator, MerR family; KEGG: eci:UTI89_C3737 2.1e-05 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG4978 Transcriptional regulator, effector-binding domain/component; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.860
EDS73843.1
Transcriptional regulator, MerR family; KEGG: vfi:VFA0114 0.00072 methyltransferase K00599; COG: COG4978 Transcriptional regulator, effector-binding domain/component; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.860
EDS74281.1
Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase.
       0.823
glyS
glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.815
EDS75712.1
Cyclic nucleotide-binding domain protein; KEGG: eci:UTI89_C3860 0.00030 crp; CRP-cAMP transcriptional dual regulator K00924; COG: COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.
   
 
 0.814
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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