Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS74281.1Hypothetical protein; COG: COG2384 Predicted SAM-dependent methyltransferase. (230 aa)    
Predicted Functional Partners:
EDS74282.1
Dinuclear metal center protein, YbgI family; COG: COG0327 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
  
 0.965
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.823
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.823
glyS
glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.815
EDS75115.1
Helix-turn-helix protein, YlxM/p13 family; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.713
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.702
EDS75407.1
COG: COG4472 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
     0.698
EDS74893.1
COG: COG1358 Ribosomal protein HS6-type (S12/L30/L7a).
  
     0.697
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
     0.662
dapD
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
  
    0.622
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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