STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdpKEGG: cpr:CPR_1776 1.5e-114 pdp; pyrimidine-nucleoside phosphorylase K00756; COG: COG0213 Thymidine phosphorylase. (416 aa)    
Predicted Functional Partners:
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 0.995
EDS74721.1
Cytidine/deoxycytidylate deaminase family protein; KEGG: spi:MGAS10750_Spy1706 1.2e-16 cytidine deaminase K01489; COG: COG0295 Cytidine deaminase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.935
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.921
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.908
deoD
KEGG: ssp:SSP0746 6.7e-71 purine nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase.
  
 
 0.888
tdk
Thymidine kinase; KEGG: bha:BH3779 1.8e-63 tdk; thymidine kinase K00857; COG: COG1435 Thymidine kinase; Psort location: Cytoplasmic, score: 8.87.
    
 0.873
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.627
EDS74304.1
Hypothetical protein.
    
  0.619
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.597
spoIIP
Stage II sporulation protein P; COG: NOG06343 non supervised orthologous group.
       0.579
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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