STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABAnti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87. (144 aa)    
Predicted Functional Partners:
EDS74309.1
STAS domain protein; KEGG: msu:MS1346 0.0064 hemH; protoheme ferro-lyase (ferrochelatase) K01772; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
 
 0.995
sigF
KEGG: hpa:HPAG1_0089 4.4e-23 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.
 
 
 0.983
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.906
EDS73819.1
KEGG: oih:OB0074 1.3e-40 stage II sporulation protein E K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.840
EDS74388.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.818
spoIIP
Stage II sporulation protein P; COG: NOG06343 non supervised orthologous group.
  
   
 0.810
spoIVA
Stage IV sporulation protein A; KEGG: cno:NT01CX_0264 0.0018 hemA; glutamyl-tRNA reductase K00155; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.808
EDS73960.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
  
 0.804
EDS73961.1
Putative sporulation transcription factor Spo0A; KEGG: ava:Ava_B0029 7.3e-05 two component transcriptional regulator, LuxR family; COG: COG0784 FOG: CheY-like receiver.
 
  
 0.804
spoVAC
Stage V sporulation protein AC; COG: NOG09745 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.
 
   
 0.802
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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