STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lepB-2Signal peptidase I; KEGG: ctc:CTC01253 9.3e-26 putative signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the peptidase S26 family. (171 aa)    
Predicted Functional Partners:
EDS75754.1
Hypothetical protein; KEGG: ctc:CTC02329 7.7e-10 putative V-type sodium ATP synthase subunit E K02121; COG: NOG31657 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
     
 0.678
sigF
KEGG: hpa:HPAG1_0089 4.4e-23 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.
     
 0.672
EDS75749.1
KEGG: ctc:CTC02332 1.0e-17 V-type sodium ATP synthase subunit C K02119; COG: COG1527 Archaeal/vacuolar-type H+-ATPase subunit C; Psort location: Cytoplasmic, score: 8.87.
    
 0.671
EDS74307.1
Hypothetical protein.
       0.661
EDS74309.1
STAS domain protein; KEGG: msu:MS1346 0.0064 hemH; protoheme ferro-lyase (ferrochelatase) K01772; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
       0.661
spoIIAB
Anti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
       0.661
atpB
ATP synthase ab domain protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
   
 
  0.651
EDS75753.1
ATP synthase, subunit F; KEGG: tko:TK1601 2.8e-08 archaeal/vacuolar-type H+-ATPase, subunit F K02122; Psort location: Cytoplasmic, score: 8.87.
    
  0.615
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.602
EDS74308.1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: gka:GK2311 1.9e-82 D-alanyl-D-alanine carboxypeptidase (penicilin binding protein) K01286; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
 
  
 0.597
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.