Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDS74371.1Hypothetical protein; KEGG: lic:LIC13172 3.7e-07 adenosine deaminase K01489; COG: NOG34388 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (928 aa)    
Predicted Functional Partners:
EDS74370.1
Hypothetical protein; KEGG: baf:BAPKO_0677 1.5e-10 recC; exodeoxyribonuclease V, gamma chain K03583; COG: COG5022 Myosin heavy chain.
       0.799
EDS74369.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.693
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.642
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
 
 0.546
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.546
EDS74372.1
Hypothetical protein; KEGG: wbr:WGLp591 0.0030 thrA; aspartate kinase / homoserine dehydrogenase K00003:K00928; COG: NOG08812 non supervised orthologous group.
       0.509
EDS75763.1
Hypothetical protein; KEGG: pub:SAR11_0453 8.8e-05 aroK; shikimate kinase K00891.
   
   0.427
EDS74818.1
KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.421
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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