STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigERNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (231 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
 
 
 0.929
EDS73819.1
KEGG: oih:OB0074 1.3e-40 stage II sporulation protein E K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.877
EDS74388.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
0.850
EDS74947.1
Putative SpoIVB peptidase; KEGG: btl:BALH_3781 6.9e-53 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.
 
   
 0.789
spoVAD
Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group.
 
    0.788
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.786
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.786
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.785
EDS74432.1
Hypothetical protein; COG: NOG05963 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 7.80.
 
    0.785
EDS73960.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.785
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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